Ternyata Tidur Menstimulasi Sel-sel Kekebalan di Otak

Penelitian telah menunjukkan bahwa selama tidur, otak bereaksi kembali, memperbarui ingatan, dan membersihkan “pemborosan.” Penelitian baru dalam model tikus menunjukkan bahwa sel-sel kekebalan khusus menjaga otak dalam keadaan baik dengan mempertahankannya selama tidur. 

Penelitian yang dilakukan selama beberapa tahun terakhir telah menemukan bukti bahwa otak mendapat kesempatan untuk menyegarkan dan memperbarui dalam banyak cara selama tidur. Sebagai contoh, para ilmuwan telah belajar bahwa otak mengkonsolidasikan ingatan yang baru terbentuk selama tidur. Mereka juga menemukan bahwa tidur memberikan peluang bagus untuk mengeluarkan “sampah” saraf. 

Sebuah tim peneliti dari Pusat Medis Universitas Rochester di New York dan Institut Teknologi Massachusetts di Cambridge telah menemukan lebih banyak tentang bagaimana pemeliharaan otak juga terjadi selama tidur.
Dalam studi mereka – yang temuannya terdapat dalam Nature Neuroscience – para peneliti bekerja dengan tikus untuk mengetahui lebih lanjut tentang bagaimana mikroglia, yang merupakan sel kekebalan yang “melayani” otak, melakukan pekerjaan pemeliharaan mereka selama tidur. “Sebagian besar telah diasumsikan bahwa gerakan dinamis dari proses mikroglial tidak peka terhadap keadaan perilaku hewan,” “Penelitian ini menunjukkan bahwa sinyal di otak kita yang memodulasi keadaan tidur dan terjaga juga bertindak sebagai saklar yang mematikan dan menghidupkan sistem kekebalan tubuh.” jelas pemimpin penulis penelitian, Prof. Ania Majewska.

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